xarelto.com Activate Card Login : How do I Activate my Xarelto Copay Card? To Activate your Xarelto Copay Card, login into Xarelto.com or Text “SAVINGS” to 27421 or call 888-XARELTO. (888-927-3586). You can also create … Continue reading xarelto.com Activate Card Login : How do I Activate my Xarelto Copay Card?